SCHEMBL16484368

SCHEMBL16484368

c1ccc(-n2cncc2-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
HTT P42858 2/20 0.41
FGFR1 P11362 1/20 0.39
IDO1 P14902 1/20 0.38
IL1R1 P14778 1/20 0.36
GPR3 P46089 1/20 0.36
GABRA5 P31644 1/20 0.36
PGR P06401 1/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 2/20 0.36
DYRK1A Q13627 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
TDO2 P48775 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764123 0.77 KDM4E (0.33) KDM4EL3MBTL1ATMHSP90AA1HSP90AB1
SCHEMBL31962 0.70 L3MBTL1 (1.00) KDM4EL3MBTL1ATMHTTIL1R1
Benzene SCHEMBL28486033 0.70 L3MBTL1 (1.00) KDM4EL3MBTL1ATMHTTIL1R1
SCHEMBL29358118 0.70 L3MBTL1 (1.00) KDM4EL3MBTL1ATMHTTIL1R1
SCHEMBL5369691 0.69 NPC1 (0.42) KDM4EL3MBTL1ATMHTTFGFR1
Pyridine SCHEMBL29038371 0.68 L3MBTL1 (0.75) KDM4EL3MBTL1ATMHTTIL1R1
Pyridine SCHEMBL30462682 0.68 L3MBTL1 (0.75) KDM4EL3MBTL1ATMHTTIL1R1
SCHEMBL10621020 0.68 L3MBTL1 (0.95) KDM4EL3MBTL1ATMHTTIL1R1
SCHEMBL28656369 0.68 L3MBTL1 (0.95) KDM4EL3MBTL1ATMHTTIL1R1
SCHEMBL18381813 0.68 L3MBTL1 (0.95) KDM4EL3MBTL1ATMHTTIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 KDM4E 502/4885L3MBTL1 1196/4885ATM 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.