Sugi Predict

Sugi Predict / Compounds / SCHEMBL16484392

SCHEMBL16484392

SCHEMBL16484392

c1ccc(-n2c3c(ccc4c3c3ccccc3n4-c3cccc(-c4ccc5oc6ccccc6c5c4)c3)c3ccc4c(c5ccccc5n4-c4cccc(-c5ccc6oc7ccccc7c6c5)c4)c32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.37
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ PLA2G2A P14555 4/20 0.36
▸ PLA2G4A P47712 4/20 0.36
▸ PLA2G10 O15496 1/20 0.36
▸ KMT2A Q03164 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ BRCA1 P38398 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ IL1R1 P14778 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484260 0.99 PLA2G2A (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL16484265 0.98 KDM4E (0.35) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL14208734 0.97 KDM4E (0.39) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL15759591 0.97 KDM4E (0.39) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL25775309 0.95 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL16484332 0.94 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL16484343 0.94 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL16484338 0.94 KDM4E (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL16484275 0.94 PLA2G2A (0.36) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL16484354 0.93 KDM4E (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 — — US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 — — US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 KDM4E 2405/4885ATM 3393/4885L3MBTL1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.