SCHEMBL16484565

SCHEMBL16484565

c1ccc(N(c2cccnc2)c2ccc3c(c2)-c2cc4ccccc4c4cccc-3c24)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HPGD P15428 3/20 0.51
TSHR P16473 2/20 0.51
MAPK1 P28482 2/20 0.51
CASP1 P29466 2/20 0.51
HIF1A Q16665 2/20 0.51
HSD17B10 Q99714 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CYP11B1 P15538 5/20 0.43
GPR84 Q9NQS5 1/20 0.35
CYP11B2 P19099 4/20 0.34
TNF P01375 1/20 0.33
TP53 P04637 1/20 0.33
CASP7 P55210 1/20 0.33
GSK3B P49841 3/20 0.32
HDAC6 Q9UBN7 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17132459 0.92 ALDH1A1 (0.48) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL24832200 0.89 ALDH1A1 (0.65) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL17132454 0.88 MAPK1 (0.41) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL20016825 0.86 ALDH1A1 (0.38) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL16484623 0.85 CYP11B1 (0.51) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL16484577 0.85 KCNA5 (0.39) ALDH1A1L3MBTL1CYP11B1CYP11B2HDAC6
SCHEMBL16485357 0.85 TNF (0.42) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL17012216 0.84 CYP11B1 (0.43) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL16484699 0.84 CYP11B1 (0.50) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL20016882 0.84 TNF (0.37) ALDH1A1HPGDTSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 ALDH1A1 1031/4885HPGD 3245/4885TSHR 4531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.