SCHEMBL16484766

SCHEMBL16484766

c1cncc(-n2c3ccc(-c4ccc5c6c(cccc46)-c4cc6ccccc6cc4-5)cc3c3cc4ccccc4cc32)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GFER P55789 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ CYP1A2 P05177 3/20 0.39
▸ METAP2 P50579 3/20 0.39
▸ CYP11B1 P15538 3/20 0.37
▸ MAPK1 P28482 4/20 0.37
▸ HSD17B10 Q99714 3/20 0.37
▸ HTT P42858 2/20 0.37
▸ GAA P10253 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ MDM2 Q00987 1/20 0.36
▸ PRKCI P41743 1/20 0.35
▸ CYP11B2 P19099 2/20 0.34
▸ ALOX12 P18054 1/20 0.34
▸ GRM1 Q13255 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ CYP17A1 P05093 1/20 0.33
▸ CYP19A1 P11511 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16485257 0.95 GFER (0.41) GFERNPSR1CYP1A2METAP2CYP11B1
SCHEMBL16484769 0.90 GFER (0.41) GFERNPSR1CYP1A2METAP2CYP11B1
SCHEMBL16484765 0.88 GFER (0.40) GFERNPSR1CYP1A2METAP2CYP11B1
SCHEMBL16485274 0.88 CYP1A2 (0.42) GFERNPSR1CYP1A2METAP2CYP11B1
SCHEMBL20016830 0.85 MAPK1 (0.34) GFERNPSR1CYP1A2METAP2CYP11B1
SCHEMBL16483126 0.85 PIK3CD (0.41) PRKCITNFL3MBTL1
SCHEMBL16483148 0.85 PIK3CD (0.41) PRKCITNFL3MBTL1
SCHEMBL16484741 0.85 GFER (0.39) GFERNPSR1CYP1A2METAP2CYP11B1
SCHEMBL16483145 0.84 L3MBTL1 (0.39) MAPK1HSD17B10HTTMAPTALDH1A1
SCHEMBL20016832 0.84 MAPT (0.36) GFERNPSR1CYP1A2METAP2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 GFER 221/4885NPSR1 4618/4885CYP1A2 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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