Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483432 | 0.94 | MAPK9 (0.38) | PIK3CDPIK3CBPIK3CGMAPK9MAPK10 | |
| SCHEMBL16484857 | 0.89 | TNF (0.39) | TNFCYP17A1CYP11B1CYP11B2MAPK14 | |
| SCHEMBL16484905 | 0.87 | TNF (0.40) | PIK3CDPIK3CBPIK3CGMAPK9MAPK10 | |
| SCHEMBL16484912 | 0.86 | TNF (0.41) | TNFCYP17A1CYP11B1CYP11B2DYRK1A | |
| SCHEMBL16484870 | 0.86 | TNF (0.36) | TNFCYP11B1CYP11B2DYRK1ANTSR1 | |
| SCHEMBL16484909 | 0.86 | TNF (0.37) | TNFCYP17A1CYP11B1CYP11B2MAPK14 | |
| SCHEMBL16484885 | 0.85 | TNF (0.35) | TNFCYP11B1CYP11B2MAPK14DYRK1A | |
| SCHEMBL16484883 | 0.85 | TNF (0.43) | TNFCYP11B1CYP11B2DYRK1ANTSR1 | |
| SCHEMBL16483728 | 0.85 | KDM4E (0.35) | TNFCYP17A1CYP11B1CYP11B2MAPK14 | |
| SCHEMBL16483433 | 0.85 | TNF (0.40) | TNFCYP17A1CYP11B1CYP11B2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |