Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | TP53 | P04637 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12776936 | 0.89 | HSD17B10 (0.64) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16484903 | 0.86 | NPC1 (0.49) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16484906 | 0.83 | MET (0.53) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL12776920 | 0.82 | ALDH1A1 (0.54) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16483027 | 0.81 | KDM4E (0.39) | HSD17B10NPC1ALDH1A1KDM4ETP53 | |
| SCHEMBL16483791 | 0.81 | KDM4E (0.39) | HSD17B10NPC1ALDH1A1KDM4ETP53 | |
| SCHEMBL12776912 | 0.81 | ALDH1A1 (0.53) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16484879 | 0.81 | ALDH1A1 (0.59) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16483748 | 0.80 | DHODH (0.42) | HSD17B10NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL16483777 | 0.80 | DHODH (0.42) | HSD17B10NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |