SCHEMBL16485012

SCHEMBL16485012

c1ccc(-n2c3c(ccc4c3c3ccccc3n4-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)c3ccc4c(c5ccccc5n4-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-5)c32)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
JAK2 O60674 1/20 0.30
JAK3 P52333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16485000 0.94 KDM4E (0.40) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26413396 0.92 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL18086297 0.91 KDM4E (0.42) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18086293 0.91 KDM4E (0.42) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18121199 0.91 KDM4E (0.42) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL24990659 0.90 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL19726500 0.90 KDM4E (0.37) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL25098793 0.88 KDM4E (0.38) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL12104914 0.88 KDM4E (0.38) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL18086265 0.87 KDM4E (0.41) KDM4EATML3MBTL1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 KDM4E 2405/4885ATM 3393/4885L3MBTL1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.