SCHEMBL18086293

SCHEMBL18086293

c1ccc(-n2c3ccccc3c3ccc4c(c5ccccc5n4-c4ccc5c(c4)C4(c6ccccc6-c6ccccc64)c4cc(-n6c7ccccc7c7c6ccc6c8ccccc8n(-c8ccccc8)c67)ccc4-5)c32)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
DUSP3 P51452 1/20 0.32
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18121199 1.00 KDM4E (0.42) KDM4EATML3MBTL1DUSP3JAK2
SCHEMBL18086297 1.00 KDM4E (0.42) KDM4EATML3MBTL1DUSP3JAK2
SCHEMBL16485000 0.96 KDM4E (0.40) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18124902 0.94 KDM4E (0.36) KDM4EATML3MBTL1DUSP3
SCHEMBL18124916 0.92 KDM4E (0.34) KDM4EATML3MBTL1DUSP3
SCHEMBL16485012 0.91 KDM4E (0.37) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL19726499 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18121226 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL18086290 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1DUSP3
SCHEMBL18086286 0.90 L3MBTL1 (0.45) KDM4EATML3MBTL1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed