Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | XIAP | P98170 | 1/20 | 0.63 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292763 | 0.83 | SLC7A5 (0.66) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL4316655 | 0.80 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL18423201 | 0.79 | SLC7A5 (0.70) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL11519315 | 0.79 | SLC7A5 (0.92) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL30468196 | 0.79 | SLC7A5 (0.70) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL9055240 | 0.79 | SLC7A5 (0.70) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL23159186 | 0.78 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL385804 | 0.78 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL8119 | 0.78 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL16398196 | 0.78 | SLC7A5 (1.00) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057687-A1 | ANTIBODY-DRUG CONJUGATE | 第一三共株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |