SCHEMBL9055240

SCHEMBL9055240

N[C@@H](Cc1ccccc1)C(=O)F

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
PTGS1 P23219 1/20 0.70
XIAP P98170 1/20 0.70
SLC15A1 P46059 1/20 0.59
LTA4H P09960 1/20 0.56
SLC1A3 P43003 2/20 0.55
SLC1A2 P43004 2/20 0.55
SLC1A1 P43005 2/20 0.55
HDAC8 Q9BY41 2/20 0.53
EPHX1 P07099 2/20 0.52
CYP1A2 P05177 1/20 0.52
LAP3 P28838 3/20 0.50
ANPEP P15144 1/20 0.50
CTSC P53634 1/20 0.50
MMP2 P08253 1/20 0.50
SRR Q9GZT4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29595350 0.89 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8118 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL16398197 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL15671104 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL837632 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL16398196 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL385804 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8119 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL1331985 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230198-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING PROTEIN NANOWIRES WITH TUNABLE FUNCTIONALITY YALE UNIVERSITY 2025-07-17 US claimed
WO-2023147365-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING PROTEIN NANOWIRES WITH TUNABLE FUNCTIONALITY YALE UNIVERSITY (US) 2023-08-03 WO claimed
US-20260146265-A1 CAS12 PROTEINS AND USES THEREOF REFORGENE MEDICINE (CN) 2026-05-28 US disclosed
EP-4737566-A1 CAS12 PROTEIN AND USE THEREOF Reforgene Medicine (CN) 2026-05-06 EP disclosed
EP-4692338-A1 CAS12 PROTEIN AND USE THEREOF Guangzhou Reforgene Medicine Co., Ltd. (CN) 2026-02-11 EP disclosed
EP-4692118-A1 ADAM9-TARGETING HUMANIZED ANTIBODY AND ANTIBODY-DRUG CONJUGATE COMPRISING SAME AND USE THEREOF Duality Biologics (Shanghai) Co., Ltd. (CN) 2026-02-11 EP disclosed
US-20260009052-A1 CAS12 PROTEINS AND USES THEREOF GUANGZHOU REFORGENE MEDICINE CO., LTD. (CN) 2026-01-08 US disclosed
US-20260001919-A1 ADENO-ASSOCIATED VIRUS WITH ENGINEERED CAPSID TENAYA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-12435327-B2 Genetically encoded tyrosine sulfation of proteins in eukaryotes TRUSTEES OF BOSTON COLLEGE (MA) 2025-10-07 US disclosed
US-20250270289-A1 SEQUENCE-DEFINED POLYMERS WITH ONE OR MORE AZIDES, METHODS OF MAKING, AND METHODS OF USE THEREOF YALE UNIVERSITY 2025-08-28 US disclosed
US-20250250585-A1 CAPSIDS FOR PLAKOPHILLIN-2 GENE THERAPY TENAYA THERAPEUTICS, INC. 2025-08-07 US disclosed
US-11408007-B2 Compositions and methods for biocontainment of microorganisms YALE UNIVERSITY (US) 2022-08-09 US disclosed
US-20220119793-A1 Genetically Encoded Tyrosine Sulfation of Proteins in Eukaryotes NATIONAL INSTITUTES OF HEALTH 2022-04-21 US disclosed
US-20220111018-A1 COMPOSITIONS AND METHODS FOR INHIBITING YEAST INFECTIONS UNIVERSITY OF IDAHO (US) 2022-04-14 US disclosed
US-20220105170-A1 AFRICAN SWINE FEVER VACCINE PHIBRO ANIMAL HEALTH CORPORATION (US) 2022-04-07 US disclosed
US-8883963-B2 Peptidomimetics with glucagon antagonistic and GLP 1 agonistic activities CADILA HEALTHCARE LIMITED (IN) 2014-11-11 US disclosed
US-8841413-B2 Antidiabetic compounds CADILA HEALTHCARE LIMITED (IN) 2014-09-23 US disclosed
US-20130225488-A1 Antidiabetic Comppounds CADILA HEALTHCARE LIMITED (IN) 2013-08-29 US disclosed
WO-1996004297-A1 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1996-02-15 WO disclosed
WO-1991005564-A1 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146265-A1 CAS12 PROTEINS AND USES THEREOF PHAX, STING1, TTLL12 SLC7A5 1547/4885ALPI 1207/4885PKM 1314/4885
US-20260001919-A1 ADENO-ASSOCIATED VIRUS WITH ENGINEERED CAPSID MYH9, MYL6, MYL12A SLC7A5 1301/4885ALPI 3321/4885PKM 3897/4885
US-20130225488-A1 Antidiabetic Comppounds GLP1R, GPR119, GIPR SLC7A5 2003/4885ALPI 2098/4885PKM 2445/4885
US-20250270289-A1 SEQUENCE-DEFINED POLYMERS WITH ONE OR MORE AZIDES, METHODS OF MAKING, AND METHODS OF USE THEREOF CPSF1, CPSF6, CPSF7 SLC7A5 444/4885ALPI 4180/4885PKM 36/4885
US-20260009052-A1 CAS12 PROTEINS AND USES THEREOF RBM12, STING1, TTLL12 SLC7A5 1370/4885ALPI 843/4885PKM 1206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.