SCHEMBL16485458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17011749	0.88	KMT2A (0.54)	KMT2AMEN1KDM4EFAAHTP53
	SCHEMBL1013959	0.86	HTT (0.59)	KMT2AMEN1MAPK1
	SCHEMBL6043781	0.86	CHKA (0.48)	CHKAKMT2AMEN1KDM4ETP53
	SCHEMBL18290565	0.83	ALDH1A1 (0.66)	CHKAKMT2AMEN1KDM4EHDAC6
	SCHEMBL28662739	0.82	FAAH (0.49)	KMT2AMEN1KDM4EFAAHTP53
	SCHEMBL378360	0.82	ALDH1A1 (0.61)	CHKAKMT2AMEN1KDM4ECHEK1
	SCHEMBL2944876	0.81	CHKA (0.66)	CHKAKMT2AMEN1KDM4EMAPK1
	SCHEMBL9996727	0.79	KDM4E (0.64)	KDM4E
	SCHEMBL17478967	0.79	ALDH1A1 (0.55)	CHKAKMT2AKDM4EHDAC6
	SCHEMBL29725216	0.78	KMT2A (0.50)	CHKAKMT2AMEN1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.