SCHEMBL16485461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8225348	0.90	KMT2A (0.58)	MEN1KMT2AKDM4ETP53MAPK1
	SCHEMBL2601932	0.83	KMT2A (0.57)	MEN1KMT2AKDM4ETP53MAPK1
	SCHEMBL9996727	0.82	KDM4E (0.64)	GAAKDM4E
	SCHEMBL21550767	0.81	KMT2A (0.50)	MEN1KMT2AGAATGFBR1ACVR1
	SCHEMBL29725216	0.81	KMT2A (0.50)	MEN1KMT2AGAATGFBR1ACVR1
	SCHEMBL19111201	0.81	LMNA (0.50)	KDM4E
	SCHEMBL1911878	0.81	CRHBP (0.55)	MEN1KMT2ATGFBR1ACVR1KDM4E
	SCHEMBL17982847	0.80	GAA (0.56)	MEN1KMT2AGAATGFBR1ACVR1
	SCHEMBL21550472	0.79	HTT (0.56)	GAATGFBR1ACVR1
	SCHEMBL21565559	0.79	KMT2A (0.50)	MEN1KMT2ATGFBR1ACVR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.