Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 7/20 | 0.41 |
| ▸ | CTSC | P53634 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478320 | 0.89 | CTSC (0.47) | TACR2CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL16478308 | 0.88 | CTSC (0.43) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478307 | 0.88 | CTSC (0.43) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478332 | 0.88 | TACR2 (0.46) | TACR2 | |
| SCHEMBL16478333 | 0.88 | TACR2 (0.46) | TACR2 | |
| SCHEMBL16485796 | 0.83 | CTSC (0.44) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478372 | 0.83 | CTSC (0.46) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478306 | 0.83 | CTSC (0.58) | TACR2CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL16485754 | 0.80 | CTSC (0.44) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16485752 | 0.79 | CTSC (0.46) | CTSCKCNH2LTB4RLTB4R2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |