Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.95 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475365 | 0.92 | FAAH (0.81) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1474935 | 0.92 | FAAH (0.81) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17652827 | 0.91 | FAAH (0.84) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1476942 | 0.91 | FAAH (0.80) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1475308 | 0.89 | RAB9A (0.79) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17510986 | 0.86 | HIF1A (0.75) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17511094 | 0.84 | HIF1A (0.73) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17079182 | 0.84 | HIF1A (0.73) | FAAHMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12349834 | 0.84 | TP53 (0.78) | FAAHRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1474855 | 0.84 | NPC1 (1.00) | FAAHMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |