Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486656 | 0.83 | SLC6A4 (0.47) | AGTR1AGTR2ADRA2CKCNH2HSP90AA1 | |
| SCHEMBL6959787 | 0.78 | HSP90AA1 (0.53) | AGTR1AGTR2KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9214231 | 0.77 | AGTR1 (0.66) | AGTR1AGTR2KCNH2TLR7POLB | |
| SCHEMBL6546225 | 0.75 | HTR2A (0.44) | TLR7POLBALDH1A1 | |
| SCHEMBL3403218 | 0.73 | SMN1; SMN2 (0.52) | AGTR1AGTR2POLBALDH1A1NPC1 | |
| SCHEMBL11014930 | 0.73 | AGTR1 (0.61) | AGTR1AGTR2KCNH2POLBALDH1A1 | |
| SCHEMBL11013827 | 0.72 | AGTR1 (0.60) | AGTR1AGTR2KCNH2POLBALDH1A1 | |
| SCHEMBL29136624 | 0.72 | AGTR1 (0.57) | AGTR1AGTR2KCNH2TLR7HSP90AA1 | |
| SCHEMBL29037510 | 0.72 | AGTR1 (0.57) | AGTR1AGTR2KCNH2TLR7HSP90AA1 | |
| SCHEMBL27714925 | 0.72 | KCNH2 (0.54) | AGTR1AGTR2KCNH2TLR7HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |