Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037510 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2KCNH2TLR7TLR8 | |
| SCHEMBL9214231 | 0.85 | AGTR1 (0.66) | AGTR1AGTR2KCNH2TLR7HSP90AA1 | |
| SCHEMBL3181792 | 0.84 | KCNH2 (0.47) | AGTR1AGTR2KCNH2TLR8HSP90AA1 | |
| SCHEMBL29136621 | 0.83 | AGTR1 (0.55) | AGTR1AGTR2KCNH2TLR7 | |
| SCHEMBL10686007 | 0.82 | AGTR1 (0.54) | AGTR1AGTR2KCNH2HSP90AA1 | |
| SCHEMBL11014930 | 0.81 | AGTR1 (0.61) | AGTR1AGTR2KCNH2HSP90AA1 | |
| SCHEMBL11013827 | 0.79 | AGTR1 (0.60) | AGTR1AGTR2KCNH2HSP90AA1 | |
| SCHEMBL5291955 | 0.79 | AGTR1 (0.60) | AGTR1AGTR2KCNH2HSP90AA1 | |
| SCHEMBL4833827 | 0.78 | ALDH1A1 (0.47) | AGTR1AGTR2KCNH2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL28122561 | 0.78 | AGTR1 (0.59) | AGTR1AGTR2KCNH2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355341-A | TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases | 纽约州立大学研究基金会 | 2024-01-05 | — | — | CN | disclosed |