Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | APBA1 | Q02410 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ACR | P10323 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17731986 | 0.86 | NPC1 (0.77) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL16486042 | 0.86 | NPC1 (0.77) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11534377 | 0.82 | SMN1; SMN2 (0.77) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL20435882 | 0.81 | MEN1 (0.78) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL17318520 | 0.80 | MEN1 (1.00) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL20620013 | 0.78 | SMN1; SMN2 (1.00) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL17732000 | 0.77 | NPC1 (0.78) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL23513412 | 0.77 | NPC1 (0.74) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11965067 | 0.77 | NPC1 (0.61) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL16486232 | 0.76 | KMT2A (0.87) | NPC1RAB9AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |