Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.87 |
| ▸ | MEN1 | O00255 | 5/20 | 0.87 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.87 |
| ▸ | THRB | P10828 | 2/20 | 0.87 |
| ▸ | MAPT | P10636 | 7/20 | 0.81 |
| ▸ | NPC1 | O15118 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | KLK7 | P49862 | 1/20 | 0.81 |
| ▸ | FAAH | O00519 | 2/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486240 | 0.88 | FAAH (0.95) | KMT2AMEN1RXFP1THRBMAPT | |
| SCHEMBL20435882 | 0.82 | MEN1 (0.78) | KMT2AMEN1RXFP1THRBMAPT | |
| SCHEMBL16486334 | 0.81 | FAAH (0.81) | KMT2AMEN1RXFP1THRBMAPT | |
| SCHEMBL15427025 | 0.79 | SMN1; SMN2 (1.00) | KMT2AMEN1RXFP1MAPTNPC1 | |
| SCHEMBL17318627 | 0.79 | FAAH (0.69) | KMT2AMEN1RXFP1MAPTNPC1 | |
| SCHEMBL16486042 | 0.77 | NPC1 (0.77) | KMT2AMEN1RXFP1MAPTNPC1 | |
| SCHEMBL17731986 | 0.77 | NPC1 (0.77) | KMT2AMEN1RXFP1THRBMAPT | |
| SCHEMBL16486346 | 0.76 | NPC1 (1.00) | KMT2AMEN1RXFP1MAPTNPC1 | |
| SCHEMBL16946642 | 0.76 | RAB9A (0.81) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL15867670 | 0.75 | NPC1 (1.00) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |