Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 4/20 | 0.32 |
| ▸ | CES1 | P23141 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744173 | 0.89 | CES2 (0.50) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL27563530 | 0.89 | CES2 (0.50) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL27282017 | 0.89 | CES2 (0.50) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL27414313 | 0.89 | CES2 (0.50) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL15489138 | 0.87 | — | — | |
| SCHEMBL27701844 | 0.83 | KDM4C (0.41) | LMNATHRB | |
| SCHEMBL14567179 | 0.81 | — | — | |
| SCHEMBL27416513 | 0.80 | FAAH (0.65) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL28083638 | 0.74 | — | — | |
| SCHEMBL28460933 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021948-A1 | AGENT FOR NUCLEATION OF POLYOLEFIN AND ELIMINATION OF FOULING IN A GAS PHASE POLYMERISATION REACTOR | POLYMER INSTITUTE BRNO, SPOL. S.R.O. (CZ) | 2015-02-19 | — | — | WO | disclosed |