Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685254 | 0.89 | SIGMAR1 (0.44) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL6831348 | 0.87 | SIGMAR1 (0.47) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL3077466 | 0.83 | SIGMAR1 (0.53) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL6832669 | 0.82 | KDM4E (0.54) | GAAKDM4ECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6101726 | 0.82 | SIGMAR1 (0.48) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL6685262 | 0.82 | SIGMAR1 (0.48) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL11024265 | 0.82 | GAA (0.77) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL1614544 | 0.80 | SIGMAR1 (0.67) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL29666490 | 0.80 | SIGMAR1 (0.67) | SIGMAR1GAANR4A1NR4A2NR4A3 | |
| SCHEMBL11416545 | 0.79 | NPSR1 (0.42) | GAATDP1KDM4ECYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021948-A1 | AGENT FOR NUCLEATION OF POLYOLEFIN AND ELIMINATION OF FOULING IN A GAS PHASE POLYMERISATION REACTOR | POLYMER INSTITUTE BRNO, SPOL. S.R.O. (CZ) | 2015-02-19 | — | — | WO | disclosed |