Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803287 | 0.89 | GAA (0.61) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL29234421 | 0.86 | GAA (0.58) | GAASIGMAR1ALDH1A1MAPTKDM4E | |
| SCHEMBL3626830 | 0.82 | SIGMAR1 (0.67) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL10958989 | 0.82 | GAA (0.52) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16487448 | 0.82 | SIGMAR1 (0.50) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL28068452 | 0.81 | SIGMAR1 (0.50) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL28317409 | 0.81 | SIGMAR1 (0.50) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL27525100 | 0.81 | SIGMAR1 (0.50) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL28447749 | 0.81 | SIGMAR1 (0.50) | GAASIGMAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL11722440 | 0.81 | SIGMAR1 (0.50) | GAASIGMAR1NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045488-B1 | WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FINISHING TEXTILES, AS WELL AS THE BETA-CHLOROETHYL-SULFONYL-METHYL-BENZOIC-ACID HALOGENIDES, AND THEIR USE AS A FIBRE-REACTIVE ANCHOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-19 | — | — | EP | claimed |