Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043982 | 0.90 | SIRT6 (0.57) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL28346802 | 0.90 | SIRT6 (0.57) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL7622596 | 0.90 | SIRT6 (0.57) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL7020890 | 0.89 | FOLH1 (0.40) | SIRT6SIRT1MAOAMAOBFOLH1 | |
| SCHEMBL12304647 | 0.86 | SIRT6 (0.49) | SIRT6SIRT1MAOAMAOBFOLH1 | |
| SCHEMBL17541390 | 0.85 | SIRT6 (0.49) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL28962963 | 0.85 | SIRT6 (0.49) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL19732599 | 0.85 | CA12 (0.43) | MAOAMAOBPAOXGGT1CA12 | |
| SCHEMBL148480 | 0.84 | FOLH1 (0.54) | SIRT6SIRT1FOLH1GSRGNAI3 | |
| SCHEMBL7076576 | 0.84 | FOLH1 (0.54) | SIRT6SIRT1FOLH1GSRGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |