Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | TLR2 | O60603 | 4/20 | 0.51 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043982 | 1.00 | SIRT6 (0.57) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL7622596 | 1.00 | SIRT6 (0.57) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL17541390 | 0.93 | SIRT6 (0.49) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL28962963 | 0.93 | SIRT6 (0.49) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL28026146 | 0.90 | RRM1 (0.53) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL1648752 | 0.90 | SIRT6 (0.43) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL23772056 | 0.88 | SIRT6 (0.43) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL7460571 | 0.87 | NOD1 (0.58) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL9791228 | 0.87 | NOD1 (0.58) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL285285 | 0.87 | NOD1 (0.58) | SIRT6SIRT1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110934863-A | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof | 阿马曾提斯公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-105142632-B | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof | 阿马曾提斯公司 | 2020-01-07 | — | — | CN | disclosed |