SCHEMBL16488248

SCHEMBL16488248

CC(C)(c1cccc(N(c2ccccc2)c2ccccc2)c1)c1cc(N(c2ccccc2)c2ccccc2)ccc1Nc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.32
MAPT P10636 3/20 0.32
GAA P10253 3/20 0.32
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NR3C2 P08235 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
GFER P55789 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
EGFR P00533 1/20 0.30
SRC P12931 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465396 0.78 NR3C2 (0.46) KDM4EMAPTGAAALDH1A1L3MBTL1
SCHEMBL17988505 0.77 ESR1 (0.44) KDM4EMAPTALDH1A1L3MBTL1NR3C2
SCHEMBL27110986 0.70 CYP2D6 (0.45) KDM4EMAPTALDH1A1L3MBTL1MEN1
SCHEMBL15709492 0.70 ALDH1A1 (0.54) KDM4EMAPTGAAALDH1A1L3MBTL1
SCHEMBL12774505 0.70 CYP2D6 (0.45) KDM4EMAPTALDH1A1L3MBTL1MEN1
SCHEMBL26404805 0.70 AKR1C3 (0.38) KDM4EMAPTGAAALDH1A1L3MBTL1
SCHEMBL22915690 0.70 MEN1 (0.46) KDM4EMAPTGAAALDH1A1L3MBTL1
SCHEMBL22600022 0.70 ALDH1A1 (0.46) KDM4EMAPTGAAALDH1A1L3MBTL1
SCHEMBL30679845 0.70 ALDH1A1 (0.46) KDM4EMAPTGAAALDH1A1L3MBTL1
SCHEMBL23620357 0.70 ABCG2 (0.43) KDM4EMAPTGAAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2837622-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2015-02-18 EP disclosed