SCHEMBL465396

SCHEMBL465396

CC(C)(c1ccccc1)c1ccc(Nc2ccc(C(C)(C)c3ccccc3)cc2C(C)(C)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 3/20 0.46
ALDH1A1 P00352 5/20 0.43
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
CYP3A4 P08684 2/20 0.43
GAA P10253 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
GFER P55789 1/20 0.41
KMT2A Q03164 1/20 0.41
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
AKR1C3 P42330 3/20 0.38
AKR1C2 P52895 3/20 0.38
ALOX15 P16050 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
TSHR P16473 2/20 0.34
ALOX12 P18054 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11806715 0.82 NR3C2 (0.45) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL22432192 0.81 CNR1 (0.44) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL12190496 0.81 MEN1 (0.46) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL158574 0.80 NR3C2 (0.60) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL11801883 0.78 AKR1C3 (0.59) NR3C2MEN1MAPTGFERKMT2A
SCHEMBL16488248 0.78 KDM4E (0.32) NR3C2ALDH1A1CYP3A4GAAL3MBTL1
SCHEMBL1576428 0.78 ALDH1A1 (0.59) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL24137225 0.77 AKR1C3 (0.42) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL22432445 0.77 AKR1C3 (0.42) NR3C2ALDH1A1ESR1ESR2CYP3A4
SCHEMBL24318168 0.77 ALDH1A1 (0.44) ALDH1A1CYP3A4GAAL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022128171-A1 THERMOPLASTIC MOLDING COMPOSITION HAVING GOOD MECHANICAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2022-06-23 WO disclosed
EP-4015550-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
EP-2553021-B1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2014-05-07 EP disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
EP-2553021-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-02-06 EP disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-8197715-B2 Thermoplastic moulding compositions having improved ductility BASE SE (DE) 2012-06-12 US disclosed
WO-2012007301-A3 FOAM ENHANCEMENT OF FATTY ACYL GLYCINATE SURFACTANTS UNILEVER PLC (GB) 2012-05-10 WO disclosed
EP-2257597-B1 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2011-11-30 EP disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
WO-2008074687-A2 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2008-06-26 WO disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0780340-B1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORP (US) 2002-03-20 EP disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0509282-B1 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF AG (DE) 1996-07-24 EP disclosed
EP-0586985-A1 Stabilized Polyamide/Polyphenylene ether mouldings BASF Aktiengesellschaft (DE) 1994-03-16 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed
US-3751472-A 2,4,4'-TRIS-(ALPHA,ALPHA-DIMETHYLBENZYL)DIPHENYLAMINE UNIROYAL CHEMICAL COMPANY, INC. 1973-08-07 US disclosed