Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26083529 | 0.70 | MEN1 (0.42) | HTTSMN1; SMN2 | |
| SCHEMBL26311628 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL12657789 | 0.66 | — | — | |
| SCHEMBL18314602 | 0.65 | MEN1 (0.44) | SMN1; SMN2 | |
| SCHEMBL26082806 | 0.65 | HTR1A (0.33) | HTR7 | |
| SCHEMBL26544451 | 0.63 | NR1H4 (0.50) | — | |
| SCHEMBL10332053 | 0.63 | SMN1; SMN2 (0.43) | SMN1; SMN2 | |
| SCHEMBL19187802 | 0.63 | ALDH1A1 (0.33) | SMN1; SMN2EGFR | |
| SCHEMBL24877371 | 0.63 | SMN1; SMN2 (0.47) | SMN1; SMN2SIRT2HTR7 | |
| SCHEMBL25689265 | 0.61 | ALDH1A1 (0.39) | HTTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203415-B1 | (CYCLOPROPYL-PHENYL)-PHENYL-OXALAMIDES, METHOD FOR THEIR MANUFACTURE AND THEIR APPLICATION AS MEDICINES | SANOFI SA (FR) | 2016-10-26 | — | — | EP | disclosed |
| EP-2683700-B1 | TETRA-SUBSTITUTED OXATHIAZINE DERIVATIVES, METHOD FOR THEIR PREPARATION, THEIR USAGE AS MEDICAMENT AND MEDICAMENT CONTAINING SAME AND ITS USE | SANOFI SA (FR) | 2015-02-18 | — | — | EP | disclosed |