Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544700 | 0.81 | ALDH1A1 (0.46) | ALOX5ALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL5681948 | 0.80 | ALOX5 (0.42) | HPGDALOX5ALDH1A1TP53TDP1 | |
| SCHEMBL16488327 | 0.79 | ALOX5 (0.44) | HPGDALOX5ALDH1A1TP53MAPT | |
| SCHEMBL7534719 | 0.73 | ALOX5 (0.39) | ALOX5ALDH1A1TP53MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL6111921 | 0.69 | ALOX5 (0.39) | ALOX5ALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL250872 | 0.68 | ALDH1A1 (0.52) | ALDH1A1TP53TDP1CYP3A4MAPT | |
| SCHEMBL8342856 | 0.68 | ALDH1A1 (0.47) | HPGDNPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL8171774 | 0.68 | ALDH1A1 (0.52) | HPGDNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL3997515 | 0.67 | ALOX5 (0.47) | HPGDRAB9AALOX5ALDH1A1TDP1 | |
| Ether SCHEMBL6687627 | 0.67 | CYP2A6 (0.50) | HPGDNPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |