Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.57 |
| ▸ | MC4R | P32245 | 7/20 | 0.55 |
| ▸ | MC5R | P33032 | 7/20 | 0.55 |
| ▸ | MC3R | P41968 | 7/20 | 0.55 |
| ▸ | MC1R | Q01726 | 7/20 | 0.55 |
| ▸ | TSLP | Q969D9 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193885 | 0.87 | ITGB3 (0.81) | ITGB3ITGAVITGA2BKLKB1MC4R | |
| SCHEMBL24433365 | 0.87 | ITGB3 (0.81) | ITGB3ITGAVITGA2BKLKB1MC4R | |
| SCHEMBL30866243 | 0.86 | HDAC3 (0.58) | ITGB3ITGAVITGA2BHDAC3HDAC4 | |
| Eptifibatide SCHEMBL8284422 | 0.85 | ITGB3 (0.82) | ITGB3ITGAVITGA2BMC4RMC5R | |
| Eptifibatide SCHEMBL29398425 | 0.85 | ITGB3 (0.82) | ITGB3ITGAVITGA2BMC4RMC5R | |
| Eptifibatide SCHEMBL15781 | 0.85 | ITGB3 (0.82) | ITGB3ITGAVITGA2BMC4RMC5R | |
| Eptifibatide SCHEMBL571287 | 0.85 | ITGB3 (0.82) | ITGB3ITGAVITGA2BMC4RMC5R | |
| SCHEMBL30169340 | 0.85 | HDAC3 (0.59) | ITGB3ITGAVITGA2BMC4RMC5R | |
| Eptifibatide SCHEMBL21753462 | 0.85 | ITGB3 (0.81) | ITGB3ITGAVITGA2BMC4RMC5R | |
| Eptifibatide SCHEMBL7107217 | 0.85 | ITGB3 (0.81) | ITGB3ITGAVITGA2BMC4RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326217-A1 | Methods and Compositions Related to Cyclic Peptide Synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-10 | — | — | US | disclosed |
| EP-1998792-B1 | METHODS AND COMPOSITIONS RELATED TO CYCLIC PEPTIDE SYNTHESIS | UNIV UTAH RES FOUND (US) | 2015-02-18 | — | — | EP | disclosed |