SCHEMBL16489191

SCHEMBL16489191

COCCCNC(=O)CCCCCN

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.73
SLC6A5 Q9Y345 2/20 0.55
HPGD P15428 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KDM4E B2RXH2 2/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PAOX Q6QHF9 2/20 0.47
ALDH1A1 P00352 3/20 0.46
FAAH O00519 1/20 0.45
MAPT P10636 1/20 0.45
KDM4A O75164 1/20 0.44
HIF1A Q16665 1/20 0.44
TET2 Q6N021 1/20 0.44
DOHH Q9BU89 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22418053 0.93 TSHR (0.68) TSHRSLC6A5HPGDMEN1KMT2A
SCHEMBL21155013 0.91 TSHR (0.70) TSHRSLC6A5HPGDMEN1KMT2A
SCHEMBL26742630 0.91 TSHR (0.59) TSHRSLC6A5HPGDMEN1KMT2A
SCHEMBL8574782 0.91 TSHR (0.88) TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL4270085 0.91 TSHR (0.88) TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL12013650 0.91 TSHR (0.88) TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL12013653 0.91 TSHR (0.88) TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL26349750 0.91 TSHR (0.60) TSHRSLC6A5HPGDMEN1KMT2A
SCHEMBL13431136 0.88 TSHR (0.76) TSHRHPGDMEN1KMT2AKDM4E
SCHEMBL16190625 0.88 TSHR (0.65) TSHRSLC6A5HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3243504-A1 IMPROVED LIPID FORMULATION Arbutus Biopharma Corporation (CA) 2017-11-15 EP disclosed
US-9114177-B2 Block copolymer having phenylboronic acid group introduced therein, and use thereof THE UNIVERSITY OF TOKYO (JP) 2015-08-25 US disclosed
US-20150051347-A1 BLOCK COPOLYMER HAVING PHENYLBORONIC ACID GROUP INTRODUCED THEREIN, AND USE THEREOF THE UNIVERSITY OF TOKYO (JP) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051347-A1 BLOCK COPOLYMER HAVING PHENYLBORONIC ACID GROUP INTRODUCED THEREIN, AND USE THEREOF SLC1A5, BPGM, BDKRB1 TSHR 1108/4885SLC6A5 810/4885HPGD 1513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.