Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.47 |
| ▸ | DRD5 | P21918 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | THPO | P40225 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211621 | 1.00 | DRD1 (0.47) | DRD1DRD5HSD17B10THPOMAPK1 | |
| SCHEMBL29462305 | 1.00 | DRD1 (0.47) | DRD1DRD5HSD17B10THPOMAPK1 | |
| Bromide SCHEMBL9405370 | 0.99 | DRD1 (0.47) | DRD1DRD5HSD17B10THPOMAPK1 | |
| SCHEMBL9405412 | 0.85 | DRD1 (0.46) | DRD1DRD5HSD17B10THPOMAPK1 | |
| SCHEMBL9404237 | 0.83 | CYP3A4 (0.39) | DRD1DRD5DRD2CYP2D6CYP3A4 | |
| Odapipam SCHEMBL7207803 | 0.83 | DRD1 (0.66) | DRD1DRD5HSD17B10THPODRD2 | |
| SCHEMBL9404411 | 0.83 | DRD1 (0.52) | DRD1DRD5HSD17B10THPOMAPK1 | |
| Odapipam SCHEMBL2056522 | 0.83 | DRD1 (0.66) | DRD1DRD5HSD17B10THPODRD2 | |
| SCHEMBL7919596 | 0.82 | DRD1 (0.67) | DRD1DRD5HSD17B10THPOMAPK1 | |
| SCHEMBL7922430 | 0.81 | DRD1 (0.55) | DRD1DRD5HSD17B10THPOMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220290159-A1 | miRNAS FOR REDUCING VENTRICLE ENLARGEMENT | St. Jude Children's Research Hpspital, Inc. (US) | 2022-09-15 | — | — | US | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |