Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489645 | 0.78 | BRD4 (0.56) | BRD4KDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL16489661 | 0.78 | BRD4 (0.53) | BRD4KCNH2KMT2ASOS1CYP2C19 | |
| SCHEMBL16489610 | 0.77 | BRD4 (0.55) | BRD4KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL16489620 | 0.77 | ALDH1A1 (0.56) | BRD4KDM4ESMN1; SMN2LMNACYP1A2 | |
| SCHEMBL16489655 | 0.75 | BRD4 (0.56) | BRD4KDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL16489613 | 0.75 | BRD4 (0.55) | BRD4KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL16489647 | 0.75 | BRD4 (0.53) | BRD4KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL16489667 | 0.74 | BRD4 (0.57) | BRD4SOS1 | |
| SCHEMBL16489648 | 0.74 | BRD4 (0.58) | BRD4KMT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL16489624 | 0.73 | BRD4 (0.56) | BRD4DCTPP1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296748-B2 | Pyridinones | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20150246919-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INT (DE) | 2015-09-03 | — | — | US | disclosed |
| US-20150051208-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051208-A1 | PYRIDINONES | MKI67, XDH, CDK6 | BRD4 1346/4885KCNH2 1318/4885DCTPP1 1193/4885 |
| US-20150246919-A1 | PYRIDINONES | MKI67, XDH, CDK6 | BRD4 1346/4885KCNH2 1318/4885DCTPP1 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.