Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.74 |
| ▸ | CES1 | P23141 | 4/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.70 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050323 | 1.00 | CES2 (0.74) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL1649013 | 1.00 | CES2 (0.74) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL1721910 | 0.91 | PTPN1 (0.63) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL1721289 | 0.89 | PTPN1 (0.61) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL974587 | 0.86 | PTPN1 (0.73) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL974588 | 0.86 | PTPN1 (0.73) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL31593848 | 0.86 | PTPN1 (0.73) | CES2CES1ALOX5PTPN1PTPN2 | |
| SCHEMBL6913431 | 0.86 | PTPN1 (0.73) | CES2CES1ALOX5PTPN1PTPN2 | |
| Katonic Acid SCHEMBL13144259 | 0.85 | CES1 (1.00) | CES2CES1ALOX5PTPN1PTPN2 | |
| Katonic Acid SCHEMBL14071724 | 0.85 | CES1 (1.00) | CES2CES1ALOX5PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139692-A2 | ANTIVIRAL TRITERPENE DERIVATIVES | SAVIRA PHARMACEUTICALS GMBH (AT) | 2010-12-09 | — | — | WO | claimed |
| US-20220296544-A1 | NANOEMULSION OF 18BETA-GLYCYRRHETINIC ACID | PROYECTOS ATSO S.A.P.I. DE C.V. (MX) | 2022-09-22 | — | — | US | disclosed |
| EP-4023219-A1 | NANOEMULSION OF 18BETA-GLYCYRRHETINIC ACID | Atso Corporate Affairs, S.A. De C.V. (MX) | 2022-07-06 | — | — | EP | disclosed |
| CN-114450001-A | 18 beta-glycyrrhetinic acid nano emulsion | 亚索事务公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-102302502-A | Compound glycyrrhizin preparation and preparation method thereof | BEIJING QINWUTIAN PHARMACEUTICAL CO LTD | 2012-01-04 | — | — | CN | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| WO-2010139692-A2 | ANTIVIRAL TRITERPENE DERIVATIVES | SAVIRA PHARMACEUTICALS GMBH (AT) | 2010-12-09 | — | — | WO | disclosed |
| CN-1827634-B | Nitrate derivatives of glycyrrhetic acid and glycyrrhetinic acid and pharmaceutical use thereof | BEIJING MEIBEITA PHARMACEUTICAL RES CO LTD | 2010-09-29 | — | — | CN | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| CN-1827634-A | Nitrate derivatives of glycyrrhetic acid and glycyrrhetinic acid and pharmaceutical use thereof | BEIJING MEIBEITA PHARMACEUTICA (CN) | 2006-09-06 | — | — | CN | disclosed |