Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.73 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | CES1 | P23141 | 5/20 | 0.67 |
| ▸ | CES2 | O00748 | 3/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 2/20 | 0.52 |
| ▸ | PTPRF | P10586 | 2/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | ACP1 | P24666 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974587 | 1.00 | PTPN1 (0.73) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL31593848 | 1.00 | PTPN1 (0.73) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL974588 | 1.00 | PTPN1 (0.73) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL29624157 | 0.87 | PTPN1 (0.62) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL1649012 | 0.86 | CES2 (0.74) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL1050323 | 0.86 | CES2 (0.74) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL1649013 | 0.86 | CES2 (0.74) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL1721910 | 0.85 | PTPN1 (0.63) | PTPN1PTPN2USP2CES1CES2 | |
| SCHEMBL178210 | 0.85 | PTPN1 (1.00) | PTPN1PTPN2USP2CES1ALOX5 | |
| SCHEMBL178211 | 0.85 | PTPN1 (1.00) | PTPN1PTPN2USP2CES1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63057519-A | — | — | None | — | — | JP | disclosed |
| WO-2004082717-A1 | PERCUTANEOUSLY ABSORBABLE ANESTHETIC | NAKANO MASAHIRO (JP) | 2004-09-30 | — | — | WO | disclosed |
| US-5622942-A | SUCH AS GLYCYRRHIZIN, GLYCYRRHETIC ACID OR ESTER | MINOPHAGEN PHARMACEUTICAL COMPANY (JP) | 1997-04-22 | — | — | US | disclosed |
| JP-S6357519-A | AGENT FOR SUPPRESSING CARCINOGENIC PROMOTOR | MINOFUAAGEN SEIYAKU HONPO:GOUSHI | 1988-03-12 | — | — | JP | disclosed |