Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177790 | 0.90 | ALDH1A1 (1.00) | ALDH1A1HSD17B10RECQLMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5198585 | 0.88 | ALDH1A1 (0.95) | ALDH1A1HSD17B10RECQLMAPTMEN1 | |
| SCHEMBL27803677 | 0.88 | ALDH1A1 (0.95) | ALDH1A1HSD17B10RECQLMAPTMEN1 | |
| Methylene Chloride SCHEMBL28851131 | 0.86 | ALDH1A1 (0.84) | ALDH1A1HSD17B10RECQLIDO1MAPT | |
| Benzene SCHEMBL27915918 | 0.86 | ALDH1A1 (0.91) | ALDH1A1HSD17B10RECQLMAPTMEN1 | |
| Methyl Alcohol SCHEMBL27669635 | 0.86 | ALDH1A1 (0.91) | ALDH1A1HSD17B10RECQLMAPTMEN1 | |
| SCHEMBL9139800 | 0.84 | ALDH1A1 (0.88) | ALDH1A1HSD17B10RECQLMAPTMEN1 | |
| SCHEMBL10703012 | 0.84 | ALOX12 (0.68) | ALDH1A1HSD17B10RECQLIDO1MAPT | |
| SCHEMBL29242 | 0.83 | CYP1A2 (0.67) | ALDH1A1HSD17B10IDO1MAPTMEN1 | |
| SCHEMBL11320631 | 0.83 | CYP1A2 (0.67) | ALDH1A1HSD17B10IDO1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |