SCHEMBL16492437

SCHEMBL16492437

C[Si](C)(C)N(/N=C(/CCC/C(=N\N([Si](C)(C)C)[Si](C)(C)C)c1ccccc1)c1ccccc1)[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
GAA P10253 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MAPT P10636 2/20 0.39
G6PC1 P35575 1/20 0.35
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGS2 P35354 1/20 0.33
PPARA Q07869 1/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
DRD4 P21917 3/20 0.32
DRD2 P14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16492438 1.00 ATM (0.41) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL16492398 0.93 ATM (0.44) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL16492397 0.93 ATM (0.44) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL15440361 0.91 L3MBTL1 (0.50) GAAL3MBTL1MAPTKMT2ALMNA
SCHEMBL15440363 0.91 L3MBTL1 (0.50) GAAL3MBTL1MAPTKMT2ALMNA
SCHEMBL16492416 0.85 ATM (0.38) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL16492415 0.85 ATM (0.38) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL14799503 0.84 ATM (0.40) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL14799502 0.84 ATM (0.40) ATMGAAL3MBTL1MAPTG6PC1
SCHEMBL15439198 0.83 ALDH1A1 (0.40) ATMGAAL3MBTL1MAPTG6PC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed