Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493139 | 0.93 | MAPT (0.45) | NOTUMMAPTRAB9APLA2G2AKDM4E | |
| SCHEMBL2533056 | 0.82 | MAPT (0.39) | MAPTRAB9APLA2G2AKDM4EALDH1A1 | |
| SCHEMBL16493155 | 0.82 | NOTUM (0.48) | NOTUMMAPTRAB9APLA2G2AKDM4E | |
| SCHEMBL16898021 | 0.82 | NOTUM (0.50) | NOTUMMAPTRAB9APLA2G2AKDM4E | |
| SCHEMBL30045094 | 0.80 | NOTUM (0.49) | NOTUMMAPTRAB9APLA2G2AKDM4E | |
| SCHEMBL17823865 | 0.80 | MAPT (0.51) | NOTUMMAPTRAB9APLA2G2AKDM4E | |
| SCHEMBL16493137 | 0.80 | NOTUM (0.49) | NOTUMMAPTRAB9APLA2G2AKDM4E | |
| SCHEMBL12563864 | 0.80 | MAPT (0.47) | MAPTRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL14812151 | 0.80 | MAPT (0.47) | MAPTRAB9AKDM4EALDH1A1TSHR | |
| SCHEMBL4650137 | 0.79 | MAPT (0.37) | MAPTRAB9AKDM4EALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022631-A1 | SUBSTITUTED BIPHENYL COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2015-02-19 | — | — | WO | disclosed |