Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493137 | 0.92 | NOTUM (0.49) | NOTUMMAPTCYP4A11CYP4F2PLA2G2A | |
| SCHEMBL30045094 | 0.92 | NOTUM (0.49) | NOTUMMAPTCYP4A11CYP4F2PLA2G2A | |
| SCHEMBL16898021 | 0.88 | NOTUM (0.50) | NOTUMMAPTPLA2G2ARAB9APOLB | |
| SCHEMBL17823865 | 0.86 | MAPT (0.51) | NOTUMMAPTPLA2G2ARAB9APOLB | |
| SCHEMBL26146688 | 0.85 | NOTUM (0.48) | NOTUMMAPTPLA2G2ARAB9APOLB | |
| SCHEMBL16397245 | 0.84 | NOTUM (0.53) | NOTUMMAPTRAB9APOLBCA12 | |
| SCHEMBL17508794 | 0.83 | PLA2G2A (0.53) | MAPTCYP4A11CYP4F2PLA2G2ARAB9A | |
| SCHEMBL30938045 | 0.82 | ALDH1A1 (0.53) | NOTUMMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL16493140 | 0.82 | NOTUM (0.43) | NOTUMMAPTPLA2G2ARAB9APOLB | |
| SCHEMBL19127993 | 0.81 | NOTUM (0.55) | NOTUMMAPTPLA2G2ARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022631-A1 | SUBSTITUTED BIPHENYL COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2015-02-19 | — | — | WO | disclosed |