Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043719 | 0.86 | SCD (0.63) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL15225478 | 0.78 | SCD (0.63) | SCDDCTPP1 | |
| SCHEMBL2470065 | 0.78 | SCD (0.73) | SCDDCTPP1 | |
| SCHEMBL3671218 | 0.75 | SCD (0.54) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2467882 | 0.75 | SCD (0.69) | SCDDCTPP1 | |
| SCHEMBL17803765 | 0.74 | SCD (0.68) | SCDDCTPP1 | |
| SCHEMBL4914115 | 0.74 | SCD (0.75) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2464906 | 0.73 | SCD (0.74) | SCDDCTPP1 | |
| SCHEMBL15225699 | 0.73 | SCD (0.64) | SCDDCTPP1 | |
| SCHEMBL14775722 | 0.72 | SCD (0.54) | SCDCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763350-B1 | NICOTINAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-12-21 | — | — | EP | claimed |