Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Finrozole SCHEMBL1658815 | 1.00 | CYP19A1 (0.62) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| Finrozole SCHEMBL2138489 | 1.00 | CYP19A1 (0.62) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8104979 | 0.89 | CYP19A1 (0.72) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL6016102 | 0.84 | CYP19A1 (0.49) | CYP19A1 | |
| SCHEMBL5583460 | 0.80 | CYP19A1 (0.44) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8408716 | 0.80 | CYP19A1 (0.62) | CYP19A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL8104665 | 0.80 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL13285157 | 0.78 | CYP19A1 (0.85) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8095364 | 0.77 | CYP19A1 (0.59) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8095377 | 0.77 | CYP19A1 (0.68) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111698987-B | Halogenated derivatives of morphinans and uses thereof | 萨鲁德医疗公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-114903046-B | Sterilization composition and application thereof | 沈阳中化农药化工研发有限公司 | 2023-06-16 | — | — | CN | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |