SCHEMBL6016102

SCHEMBL6016102

OC(Cc1ccc(F)cc1)C(c1ccccc1)n1cncn1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 14/20 0.49
MAPT P10636 1/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP26A1 O43174 1/20 0.39
SRC P12931 1/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Finrozole SCHEMBL2138489 0.84 CYP19A1 (0.62) CYP19A1
Finrozole SCHEMBL1658815 0.84 CYP19A1 (0.62) CYP19A1
Finrozole SCHEMBL1649445 0.84 CYP19A1 (0.62) CYP19A1
SCHEMBL5583460 0.80 CYP19A1 (0.44) CYP19A1MAPTMEN1KMT2A
SCHEMBL30241600 0.78 CYP19A1 (0.54) CYP19A1MAPTMEN1KMT2ACYP26A1
SCHEMBL10815039 0.77 CYP19A1 (0.58) CYP19A1MEN1KMT2A
SCHEMBL9472979 0.77 CYP19A1 (0.49) CYP19A1MAPTMEN1KMT2ACYP26A1
SCHEMBL31606566 0.76 CYP19A1 (0.51) CYP19A1MAPTMEN1KMT2ACYP26A1
SCHEMBL10838717 0.74 CYP19A1 (0.49) CYP19A1MAPTMEN1KMT2ACYP26A1
SCHEMBL6204190 0.73 MAPT (0.57) CYP19A1MAPTMEN1KMT2APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7155076-B2 Target molecules detection by waveguiding in a photonic silicon membrane THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-12-26 US disclosed