Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494619 | 0.94 | JAK2 (0.35) | JAK2DHPSPARP1TAAR1KDR | |
| SCHEMBL16494828 | 0.88 | JAK2 (0.44) | JAK2PARP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16495119 | 0.87 | CYP1A2 (0.39) | JAK2DHPSPARP1TAAR1SLC6A2 | |
| SCHEMBL16495003 | 0.86 | JAK2 (0.36) | JAK2DHPSPARP1TAAR1CYP3A4 | |
| SCHEMBL16494404 | 0.81 | JAK2 (0.44) | JAK2PARP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16494733 | 0.78 | JAK2 (0.38) | JAK2DHPSPRKCQKDM4ELMNA | |
| SCHEMBL16494693 | 0.77 | JAK2 (0.43) | JAK2PARP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16494255 | 0.75 | JAK2 (0.43) | JAK2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16494274 | 0.75 | JAK2 (0.43) | JAK2PRKCDPARP1CYP3A4CYP2D6 | |
| SCHEMBL16495136 | 0.74 | JAK2 (0.42) | JAK2PARP1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |