Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 1.00 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.71 |
| ▸ | PAM | P19021 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17812631 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL8161925 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL369211 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL8160365 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL3504178 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL1133768 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL461558 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL6027216 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL15879435 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL3677993 | 1.00 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088241-A1 | Bioreactive Agents | THE TRUSTEES OF BOSTON UNIVERSITY | 2012-04-12 | — | — | US | disclosed |
| US-20110129878-A1 | BIOREACTIVE AGENTS | THE TRUSTEES OF BOSTON UNIVERSITY | 2011-06-02 | — | — | US | disclosed |
| US-20100196988-A1 | Bioreactive Agents | THE TRUSTEES OF BOSTON UNIVERSITY | 2010-08-05 | — | — | US | disclosed |
| US-20090176279-A1 | Bioreactive agents | THE TRUSTEES OF BOSTON UNIVERSITY | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129878-A1 | BIOREACTIVE AGENTS | NEFM, TNF, GGT1 | DGKA 1361/4885DNM1 4408/4885PAM 1986/4885 |
| US-20100196988-A1 | Bioreactive Agents | NEFM, TNF, GGT1 | DGKA 1362/4885DNM1 4419/4885PAM 1984/4885 |
| US-20090176279-A1 | Bioreactive agents | NEFM, TNF, GGT1 | DGKA 1361/4885DNM1 4408/4885PAM 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.