Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.42 |
| ▸ | MC5R | P33032 | 3/20 | 0.41 |
| ▸ | MC1R | Q01726 | 3/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598783 | 0.92 | IP6K1 (0.45) | HTR6IP6K1MC5RMC1RMC3R | |
| SCHEMBL2598704 | 0.86 | PRKCQ (0.39) | MEN1KMT2ATDP1KDRPRKCQ | |
| SCHEMBL16495336 | 0.85 | HTR6 (0.43) | HTR6IP6K1MC5RMC1RMC3R | |
| SCHEMBL16494608 | 0.85 | IP6K1 (0.45) | HTR6IP6K1MC5RMC1RMC3R | |
| SCHEMBL2598814 | 0.82 | BACE1 (0.40) | TDP1CYP3A4PRKCQLMNA | |
| SCHEMBL2598672 | 0.80 | MC5R (0.46) | HTR6IP6K1MC5RMC1RMC3R | |
| SCHEMBL2598674 | 0.79 | CLK1 (0.40) | MEN1KMT2ATDP1MAPTKDR | |
| SCHEMBL16494883 | 0.79 | KDR (0.44) | TDP1KDRPRKCQLMNA | |
| SCHEMBL2598711 | 0.79 | MC5R (0.43) | HTR6IP6K1MC5RMC1RMC3R | |
| SCHEMBL14840075 | 0.78 | LMNA (0.38) | TDP1CYP3A4PRKCQLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |