Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494247 | 0.97 | HTR2A (0.44) | HTR2AHTR2CMEN1KMT2AUSP2 | |
| SCHEMBL12185437 | 0.87 | MKNK1 (0.51) | HTR2AMEN1KMT2AUSP2CYP1A2 | |
| SCHEMBL16495082 | 0.85 | SPR (0.41) | HTR2AHTR2CMEN1KMT2AUSP2 | |
| SCHEMBL12185425 | 0.84 | MTNR1A (0.43) | HTR2AMEN1KMT2AUSP2CYP1A2 | |
| SCHEMBL12185423 | 0.84 | CDK2 (0.52) | HTR2AMEN1KMT2AUSP2CYP1A2 | |
| SCHEMBL12185439 | 0.84 | SPR (0.48) | HTR2AHTR2CMEN1KMT2AUSP2 | |
| SCHEMBL16495008 | 0.82 | SPR (0.40) | HTR2AHTR2CMEN1KMT2AUSP2 | |
| SCHEMBL2598612 | 0.81 | SPR (0.47) | HTR2AHTR2CMEN1KMT2AUSP2 | |
| SCHEMBL12185470 | 0.80 | CYP1A2 (0.46) | HTR2AMEN1KMT2AUSP2CYP1A2 | |
| SCHEMBL12185481 | 0.78 | PRKCQ (0.40) | MEN1KMT2ALMNACCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |