Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839111 | 0.91 | LPAR1 (0.41) | ALOX5ALOX5APP2RX7LPAR1LPAR3 | |
| SCHEMBL2762347 | 0.91 | LPAR1 (0.41) | ALOX5ALOX5APP2RX7LPAR1LPAR3 | |
| SCHEMBL16060874 | 0.90 | LPAR1 (0.42) | ALOX5ALOX5APP2RX7LPAR1LPAR3 | |
| SCHEMBL16496719 | 0.88 | TSHR (0.38) | ALOX5ALOX5APP2RX7LPAR1LPAR3 | |
| SCHEMBL2837769 | 0.86 | P2RX7 (0.37) | ALOX5ALOX5APP2RX7LPAR1LPAR3 | |
| SCHEMBL2761549 | 0.86 | TSHR (0.41) | LPAR1LPAR3LPAR2TSHRKDM4E | |
| SCHEMBL2834340 | 0.86 | LPAR1 (0.41) | ALOX5ALOX5APP2RX7LPAR1LPAR3 | |
| SCHEMBL2836944 | 0.84 | KMT2A (0.38) | P2RX7LPAR1LPAR3LPAR2TSHR | |
| SCHEMBL2838361 | 0.80 | P2RX7 (0.37) | P2RX7LPAR1LPAR3LPAR2SMN1; SMN2 | |
| SCHEMBL2762863 | 0.80 | ALDH1A1 (0.40) | ALOX5ALOX5APP2RX7LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | LPAR1, LPAR2, LPAR4 | ALOX5 206/4885ALOX5AP 154/4885P2RX7 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.