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Deslorelin

Deslorelin

SCHEMBL1649660

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GNRHR

The experimentally established mechanism targets of Deslorelin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GNRHR known ✓ P30968 2/20 0.86
▸ ABCC2 Q92887 1/20 0.84
▸ PTGS1 P23219 1/20 0.80
▸ APLNR P35414 4/20 0.65
▸ CXCR4 P61073 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leuprolide SCHEMBL7751433 1.00 GNRHR (0.86) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL10061885 1.00 GNRHR (0.86) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL4585 1.00 GNRHR (0.86) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL21540132 1.00 GNRHR (0.86) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL6448301 0.99 GNRHR (0.86) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL3915060 0.99 GNRHR (0.86) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL847084 0.99 ABCC2 (0.87) GNRHRABCC2PTGS1APLNRCXCR4
SCHEMBL21109135 0.99 GNRHR (0.84) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL570851 0.99 ABCC2 (0.87) GNRHRABCC2PTGS1APLNRCXCR4
Leuprolide SCHEMBL3174 0.99 ABCC2 (0.87) GNRHRABCC2PTGS1APLNRCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024082230-A1 USE OF DESLORELIN ACETATE IN PREPARATION OF DRUG FOR REGULATING SEXUAL CYCLE OF ANIMAL 中国科学院深圳先进技术研究院 2024-04-25 — — WO disclosed
CN-115671255-A Application of dessertraline acetate in preparation of drugs for regulating animal sexual cycles 中国科学院深圳先进技术研究院 2023-02-03 — — CN disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 — — US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 — — US disclosed
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