Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HBB | P68871 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nogalamycin SCHEMBL4472 | 1.00 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| Nogalamycin SCHEMBL4473 | 1.00 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| Nogalamycin SCHEMBL29356331 | 1.00 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| Nogalamycinic Acid SCHEMBL30055177 | 0.95 | HSD17B10 (0.65) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL18567081 | 0.91 | HSD17B10 (0.72) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| Disnogamycin SCHEMBL29390994 | 0.88 | HSD17B10 (0.55) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| Disnogamycin SCHEMBL26459009 | 0.88 | HSD17B10 (0.55) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL3345418 | 0.84 | HSD17B10 (1.00) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL11468050 | 0.84 | HSD17B10 (1.00) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 | |
| SCHEMBL18593716 | 0.77 | HSD17B10 (0.52) | HSD17B10ALDH1A1CYP1A2HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337682-A1 | BACILLUS VELEZENSIS, FERMENTATION METHOD, FERMENTATION PRODUCT AND ITS APPLICATION | HUNAN VEGETABLE RES INSTITUTE (CN) | 2023-10-26 | — | — | US | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |