Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16497377 | 0.95 | TSHR (0.35) | TSHRTHRBOPRM1TRPM8EPHX1 | |
| SCHEMBL16497615 | 0.95 | TSHR (0.35) | TSHRTHRBOPRM1TRPM8EPHX1 | |
| SCHEMBL16497564 | 0.92 | TSHR (0.32) | TSHRTHRBOPRM1TRPM8LMNA | |
| SCHEMBL16497029 | 0.86 | TSHR (0.32) | TSHRTHRBOPRM1TRPM8LMNA | |
| SCHEMBL16496993 | 0.86 | TSHR (0.32) | TSHRTHRBOPRM1TRPM8LMNA | |
| SCHEMBL16497178 | 0.80 | — | — | |
| SCHEMBL562896 | 0.76 | TSHR (0.50) | TSHRTHRBDNM1LMNA | |
| SCHEMBL12311680 | 0.75 | EPHX1 (0.38) | TSHRTHRBOPRM1TRPM8EPHX1 | |
| SCHEMBL16497357 | 0.75 | — | — | |
| SCHEMBL16497570 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313184-A1 | INSULATING FILM MATERIAL, AND FILM FORMATION METHOD UTILIZING THE MATERIAL, AND INSULATING FILM | TAIYO NIPPON SANSO CORPORATION (JP) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313184-A1 | INSULATING FILM MATERIAL, AND FILM FORMATION METHOD UTILIZING THE MATERIAL, AND INSULATING FILM | APOB, HMGCR, SREBF1 | TSHR 4632/4885THRB 3617/4885OPRM1 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.