SCHEMBL16498011

SCHEMBL16498011

O=C(O)CC(CC1CCC1)C(=O)N(c1nc(-c2ccccc2-c2ccc(N3CCCC3=O)nc2)cs1)C1CC1

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 11/20 0.73
CNR2 P34972 1/20 0.39
USP19 O94966 1/20 0.33
SLC12A5 Q9H2X9 2/20 0.33
KDM1A O60341 2/20 0.32
UCHL1 P09936 1/20 0.31
ITGB3 P05106 1/20 0.31
ITGA2B P08514 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16498009 1.00 FFAR2 (0.73) FFAR2CNR2USP19SLC12A5KDM1A
SCHEMBL1916204 0.99 FFAR2 (0.75) FFAR2CNR2USP19SLC12A5KDM1A
SCHEMBL1917149 0.99 FFAR2 (0.75) FFAR2CNR2USP19SLC12A5KDM1A
SCHEMBL1915975 0.96 FFAR2 (0.74) FFAR2CNR2USP19SLC12A5KDM1A
SCHEMBL1915979 0.96 FFAR2 (0.74) FFAR2CNR2USP19SLC12A5KDM1A
SCHEMBL2397473 0.94 FFAR2 (0.67) FFAR2CNR2USP19SLC12A5
SCHEMBL1916323 0.94 FFAR2 (0.67) FFAR2CNR2USP19SLC12A5
SCHEMBL2402532 0.94 FFAR2 (0.66) FFAR2CNR2SLC12A5KDM1AITGB3
SCHEMBL1915693 0.94 FFAR2 (0.66) FFAR2CNR2SLC12A5KDM1AITGB3
SCHEMBL1916342 0.93 FFAR2 (0.65) FFAR2CNR2SLC12A5KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011151434-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2011-12-08 WO claimed
WO-2011151434-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2011-12-08 WO disclosed