Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 11/20 | 0.74 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | USP19 | O94966 | 1/20 | 0.32 |
| ▸ | SLC12A5 | Q9H2X9 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915979 | 1.00 | FFAR2 (0.74) | FFAR2CNR2USP19SLC12A5MMP2 | |
| SCHEMBL1917149 | 0.98 | FFAR2 (0.75) | FFAR2CNR2USP19SLC12A5MMP2 | |
| SCHEMBL1916204 | 0.98 | FFAR2 (0.75) | FFAR2CNR2USP19SLC12A5MMP2 | |
| SCHEMBL16498011 | 0.96 | FFAR2 (0.73) | FFAR2CNR2USP19SLC12A5ITGB3 | |
| SCHEMBL16498009 | 0.96 | FFAR2 (0.73) | FFAR2CNR2USP19SLC12A5ITGB3 | |
| SCHEMBL1917141 | 0.95 | FFAR2 (0.67) | FFAR2CNR2SLC12A5 | |
| SCHEMBL1917136 | 0.95 | FFAR2 (0.67) | FFAR2CNR2SLC12A5 | |
| SCHEMBL1916323 | 0.92 | FFAR2 (0.67) | FFAR2CNR2USP19SLC12A5 | |
| SCHEMBL2397473 | 0.92 | FFAR2 (0.67) | FFAR2CNR2USP19SLC12A5 | |
| SCHEMBL1916167 | 0.92 | FFAR2 (0.63) | FFAR2CNR2USP19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364297-A1 | Compounds, pharmaceutical composition and methods for use in treating metabolic disorders | Euroscreen S.A. (BE) | 2011-09-14 | — | — | EP | claimed |
| WO-2011076734-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES | EUROSCREEN S.A. (BE) | 2011-06-30 | — | — | WO | claimed |
| WO-2011076732-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING GASTROINTESTINAL DISORDERS | EUROSCREEN S.A. (BE) | 2011-06-30 | — | — | WO | claimed |
| WO-2010066682-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2010-06-17 | — | — | WO | claimed |